Indore becomes the first city to offer non surgical weight loss
Indore becomes the first city in the country to offer non surgical method of weight loss. City based Mohak Bariatrics and Robotics one of the country’s leading weight loss surgery centre has come up with the modality, Endoscopic sleeve gastroplasty, a novel procedure which was performed for the first time in India at this hospital.
The procedure was performed by Dr. Mohit Bhandari and Dr. Manoel Galvao Neto from Brazil. The patient who was operated upon was 87 kg weight with BMI 32.7
Patient was a type 2 diabetic since last 5 years.
According to bariatric surgeon Dr. Mohit Bhandari, this is a non invasive method for treatment of obesity.
According to him, in this procedure capacity of the stomach is reduced by plication taking sutures all around stomach to reduce its size.
Dr. Bhandari says patients can lose 15-25 kg depending on multiple factors through this procedure.
He adds bariatric surgery is a more radical approach towards weight loss which incorporates both restrictive and Malabsorptive component.
We all need a bridge therapy between medical and surgical therapy and endoscopic sleeve gastroplasty is that option.
The cost of the procedure will be around 2.5 lakh rupees.
Dr. Bhandari is one of the pioneers in bariatric surgery and has singularly performed more than 8000 bariatric and Robotic procedures which is one of the highest volume in Asia.
Source: https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/indore-becomes-the-first-city-to-offer-non-surgical-weight-loss/articleshow/62581891.cms
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Wrinkles treatment: New type of Botox discovered from animal gut bacteria
Scientists have discovered a new source of neurotoxin, known for its paradoxical ability to remove wrinkles yet cause an illness associated with food poisoning from a strain of animal gut bacteria, a finding that can potentially expand its therapeutic applications.
Clostridium botulinum toxin was able to jump into bacteria called Enterococcus faecium, through plasmids, mobile structures that contain DNA independently of the chromosomes and can be swapped from one bacterium to another, the study showed.
Enterococci are hardy microbes that thrive in the gastrointestinal tracts of nearly all land animals, including our own, and generally cause no harm.
But their ruggedness has lately made them leading causes of multi-drug resistant infections, especially in settings like hospitals where antibiotic use disrupts the natural balance of intestinal microbes.
“This is the first time that an active botulinum toxin has been identified outside of Clostridium botulinum and its relatives, which are often found in soil and untreated water,” said Andrew Doxey, a bioinformatics professor at the University of Waterloo.
“Its discovery has implications in several fields, from monitoring the emergence of new pathogens to the development of new protein therapeutics — it’s a game changer,” Doxey added.
Over the past 20 years, botulinum toxin type A, known as Botox, has been used for a growing number of therapeutic applications including treatment for migraines, leaky bladders, excessive sweating and cardiac conditions.
In the study, which appeared in the journal Cell Host and Microbe, the researchers were able to sequence the genome of the E. faecium bacteria drawn from cow faeces, and found the gene for botulinum toxin in the bacterial strain.
They noted that the botulinum toxin was likely transferred from C. botulinum bacteria in the environment into the E. faecium bacteria in the cow’s gut, showing that the toxin can be transferred between very different species.
“The botulinum toxin is a powerful and versatile protein therapeutic,” said Michael Mansfield, a Biology doctoral student at the varsity.
“By finding more versions of the toxin in nature, we can potentially expand and optimise its therapeutic applications even further.”
Source: http://zeenews.india.com/health/new-type-of-botox-discovered-from-animal-gut-bacteria-2076794
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New eczema therapy reduces asthma severity in kids
Scientists have discovered insights for a possible new therapy for eczema that also reduces the severity of asthma in children.
The findings, published in the Journal of Investigative Dermatology, are an important next step in understanding the relationship between the two inflammatory diseases and to developing effective therapies.
Children with atopic dermatitis (AD), a type of eczema of the skin, show an increased risk of developing asthma later in life.
House dust mites are known culprits in the development of both AD and asthma, as exposure to the mites induces inflammation.
The researchers from VIB, the Flanders Institute for Biotechnology in Belgium, created a mouse model to look further into the relationship between the two diseases.
“As predicted, our test showed that house dust mite- induced skin inflammation leads to aggravated levels of allergic airway inflammation,” Julie Deckers, from VIB.
“Yet, to our surprise, this response significantly differs from the reaction to direct exposure of house dust mites in the lungs without prior skin inflammation. These results have given us a deeper understanding of the complexity of the atopic march,” Deckers said.
The challenge, however, was to investigate whether the relief of skin inflammation might influence the subsequent development of asthma.
The team therefore combined two anti-inflammatory compounds—orticosteroids and PPAR agonists—into one potential treatment in mice.
“The combined therapy effectively alleviated AD, but was insufficient at preventing allergic asthmatic response in the lungs,” said Deckers.
“However, the treatment did significantly reduce the severity of the asthma by counteracting one aspect of the specific immune response in the lungs. In this way, the therapy represents a potent remedy against allergic skin inflammation and the aggravation of atopic march,” Deckers added.
Photo source: Thinkstock
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New ‘smart’ material to help fight tooth decay
Scientists have developed a filling material with tiny particles made by self-assembly of antimicrobial drugs which is designed to stop bacteria in its tracks.
Toronto: Researchers have developed a ‘smart’ material to minimise new cavities caused by bacteria digging under the dental fillings.
These recurrent caries affect 100 million patients every year and cost an additional USD 34 billion to treat, researchers said.
In the study published in the journal Scientific Reports, researchers from the University of Toronto in Canada have proposed a novel solution.
They have developed a filling material with tiny particles made by self-assembly of antimicrobial drugs which is designed to stop bacteria in its tracks.
These particles may solve one of the biggest problems with antibacterial filling materials: storing enough drug within the material to be effective for someone’s entire life.
“Adding particles packed with antimicrobial drugs to a filling creates a line of defence against cavity-causing bacteria,” said Professor Ben Hatton.
“Traditionally there has only been enough drug to last a few weeks. We discovered a combination of drugs and silica glass that organise themselves on a molecule-by-molecule basis to maximise drug density, with enough supply to last years,” said Hatton.
The discovery of using antimicrobials which self-assemble means the team can pack 50 times as much of the bacteria-fighting drugs into the particles, researchers said.
“We know very well that bacteria specifically attack the margins between fillings and the remaining tooth to create cavities,” said Professor Yoav Finer.
“Giving these materials an antimicrobial supply that will last for years could greatly reduce this problem,” said Finer.
The research team plans on testing these new drug-storing particles in dental fillings, monitoring their performance when attacked by bacteria and saliva in the complex environment in the mouth.
With some fine-tuning, the new ‘smart’ material could create a stronger filling and fewer trips to the dentist, researchers said.
Source: http://zeenews.india.com/health/new-smart-material-to-help-fight-tooth-decay-2077504
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Teens glued to smartphones have 400% more chance of getting brain cancer
There is a 400% increase in the risk of brain cancer among teenagers due to excessive use of smart phones, says Professor Girish Kumar of the Indian Institute of Technology, Mumbai.
The scientist urged the smart phone users not to take lightly the latest warnings pertaining to “hidden dangers” of technology, which stem from indiscriminate use of such devices.
He also categorically warned people from using smart phones for more than 30 minutes a day.
Prof Girish Kumar from the Electrical Engineering Department of IIT Mumbai had recently submitted a report to the central government on the serious health hazards of excessive use of latest technology.
He pointed out that the release of free radicals into the human body due to excessive use of cell phones was also causing irreversible damage to male fertility.
The scientist stressed that children, in particular, were suffering grave threats to their health as “a child’s skull is thinner and easily penetrated by radiation”.
Cell phone radiations are also causing serious effects on animal and plant life, he said.
Talking about the adverse impact of indiscriminate use of latest technology on youngsters, Prof Kumar said there was a 400 per cent increase in the risk of brain cancer among teenagers due to excessive use of smart phones.
“Such radiation is causing irreversible damage to the human DNA, especially of youngsters. It is also responsible for a steep increase in sleep disorders and neurodegenerative diseases, Alzheimer and Parkinson’s disease,” he said.
The IIT professor added that one cannot wish away the latest technological developments, but it would be a fatal error if the society was not made aware of the serious health hazards, emanating from unbridled use of technology.
Source: http://www.dnaindia.com/health/report-teens-glued-to-smartphones-have-400-more-chance-of-getting-brain-cancer-iit-professor-2563167
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