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THE BEST KNEE SURGERY

We are surrounded by fast- growing technology all around and often find it difficult to keep pace. Twenty five years ago, talking to another person involved booking a trunk call and waiting endlessly. Todayone can share pictures with an entire group of people while on the move. Development has revolutionised every aspect of life and healthcare is no different. Howeverit is not that keeping in contact over mobile phones betters relationships between people. Nothing can replace a one to one meeting and a face to face conversation. Similarly as regards a medical problem, even though vast knowledge could be available on the Internet by uploading reports, thorough clinical examination by a good doctor is irreplaceable and invaluable.

Surgeries on joints have improved the quality of life of millions of patients worldwide and are now rated among the best of all types of planned surgery. Like some people accept technology more easily than others, there are many who would rather suffer a lot of disability than go through surgery for fear of becoming worse. At the same time, there is a plethora of sites advertising different treatments claiming success, which would definitely confuse people. There is often no mechanism of getting the correct scientific and evidence based information.In this scenario, I have tried to address certain issues below on aspects related to surgery. As surgical techniques have evolved, concrete proof on each of these aspects has emerged, that too not in relation to a small group of patients but in various different environments all around the world.

To have or not to have surgery

There are few causes for which surgery is absolutely and urgently necessary on knees e.g. Fractures when the blood vessels are injured as well. Recommendation for surgery should be made only after discussing the merits and demerits of the procedure, and that too after clinical examination, not on the basis of reports. Commercialisation of healthcare has brought about practises where patients are coerced into immediate/ early surgery. There is evidence that most cases of ligament injury will not do well with immediate unplanned surgery, even Arthroscopy. If done immediately after knee injuries, they cause more stiffness and pain. In knee injuries where there are none or minor fractures, early rehabilitation by return to movement of the knee is the key. The majority of ligament injuries heal on their own. Splints, plasters or knee caps are grossly overused. They are known to weaken the muscles over time and would cause further predisposition to injury or worsen arthritis in the case of the young or older patient respectively. Correct rehabilitation after an injury should make the knee feel 70-80% better. One must pay attention to symptoms if present about a month or later after injury and consult the right specialist at that stage. If seemingly minor problems are neglected, they can progress to irreversible joint damage over time. Many people get arthritis very early in this country as mechanisms for recognition of early damage are not in place.

In the case of arthritis, we see various remedies- both operative and non- operative being advertised. Before going for any of these, one must question the scientific proof and explore side effects. Any knee pain is described as arthritis. In my practice most 40 to 60 year olds presenting with knee pain are due to muscular problems or moderate arthritis at the most, which can be very well managed without surgery. In such cases exercises have a better role than medications. Traditional systems of medicine can work very well if implemented in pure holistic form, without mixing treatments.

Surgery – joint replacementon the other hand, is not for any joint pain. It works very well for pain and disability associated with severe end stage arthritis I.e. Bone surfaces badly destroyed, not otherwise. There is a lot of research on unsuccessful joint replacement surgery and specialists practising exclusively in this field could reasonably predict after careful discussion and examination whether a patient might benefit or not.The commonest reason for unsatisfied patients is improper selection of patient for surgery. When the arthritis is severe, it is pointless to roam around looking for ‘magic’ cures, as different medicines (allopathic or traditional medicine) all have a side effect profile. Arthroscopy (keyhole surgery) is something with almost no risk, but works well for ligament and cartilage injuries, not for arthritis. If advised at age of 40 or less, there is little to think against it as there is no risk or downside to it. In fact, it can be done as a day case with no overnight hospital stay. Rehabilitation in such case should be quick and the person can even get back to work within a week– seems like hardly any surgery at all. On the other hand, keyhole surgery after the age of 40 may not always be so advantageous, as the presence of arthritis might make it’s success limited.

Timing

Surgery, if and when advised, should be planned with a clear understanding of what is wrong and what one aims to achieve. The practice of admitting a patient in hospital first, deciding on joint surgery and undertaking it with no clear idea of timelines must be condemned, as results are far poorer in scientific literature across the world. The best results are when a patient has had enough opportunity to contemplate what they are undergoing, had discussions with close family and friends who will contribute towards their support and rehabilitation after surgery.
There is enough proof to show that knee surgery is not as successful when a patient is not themselves ready to undergo it. Hence no one should be forced unless they make the choice on their own accord.Most timings can be planned as per family logistics over a few months’ time.

Investigations and MRI
Development has brought about endless tests which are easily available even in smaller cities. Blood tests and MRI of knees are recommended at a very early and often unnecessary stage. These often do not contribute anything towards the patients’ treatment and reportscommonly have errors when the MRIs are low resolution poor quality images. There is also a known limit of diagnostic accuracy with these and errors in imaging could be 20% or higher. I would like to strongly stress that any blood test report or image in the world has relevance only in the clinical context I.e. if it can be correlated with a problem following discussion with and examination of the patient.
If and when the same patient presents for surgery, MRI done many months in advance might be irrelevant if the clinical picture has changed by then. Hence I would strongly advise patients to know from their specialist doctor why a specific test or MRI is being requested and whether it is likely to result in surgery, with the urgency thereof. If the patient has logistic constraints or is keen to try non- surgical treatment, there is often no need to undertake MRI. It could be postponed to a time when situations change.

Worsening the situation
There’s no doubt that overt advertisement of healthcare commodities confuse patients when they have to make a choice for their treatment. The easy way found by most is to take various opinions from multiple places and compare costs. There is nothing wrong in seeking opinions from practitioners of different principles too. However patient compliance with all the treatmentsin such cases is often very low. One must therefore follow advice given by the doctor for the recommended period before deciding whether it works or not.
The onus is on the patient to approach a particular practitioner. Instead of roaming randomly from pillar to postand taking a mixture of treatments from different places, often resulting in greater side effects than benefit. A literate person could check whether the doctor being approached is the best suited for their specific problem in terms of speciality practice. When comparing prices, the patient must ensure that they are comparing like and like. There is no point in compromising on certain theatre standards purely to decrease the cost and also cut corners by undertaking certain surgeries in theatres not correctly equipped. Bigger setups could cost more but would certainly be safe. Technical details are difficult to explain to patients. It will help patients to frankly discuss above matters with their respective specialist and understand nuances rather than run around with half baked knowledge. There are different ways of decreasing costs which can be discussed as per the individual’s problem.

Cost of Surgeryand Implants
Many patients are convinced that they want ‘imported’ implants, but would like compromise on other aspects in hospital to reduce the cost. This notion is incorrectly founded, as there are now some good quality implants being manufactured indigenously. There are similarly a number of implants manufactured abroad that do not have much scientific research backing.
In my practice, it is not expense, but clinical need that determines what implant a patient should have. There are various implant designs registered successful in the long term on international joint registries. It is best to select one of these or an indigenous one based on similar engineering design principles, which every joint surgeon must be well versed with. Within these, there are cheaper and more expensive options.
There are packages available in most specialist centres where costs can be cut. It is not worth further compromising on these in smaller setups as risks of complications then increase drastically.There are schemes available through which the State pays a major chunk of the cost, even when the patient is not previously medically insured.

Recovery after Surgery, Blood transfusion and ICU stay
Best practice techniques internationally have enabled ‘Enhanced Recovery’ in planned joint surgeries I.e. Patients walk the same day of surgery and achieve a level of activity that they can manage independently at home following discharge. This technique has shown immense cost benefit by reduction of hospital stay and the requirement for additional rehabilitation measures at home after release from hospital.
Similarly, with modern techniques, we have seen that requirement for blood transfusion after surgery in our practice is less than 5%. ICU stay is ‘0’ for straight primary operations. There are guidelines established in specialty centres around the world for joint surgeries so as to minimise complications.These methods have revolutionised such apparently ‘major’ surgery. It is not worth doing such surgeries if these standards are not adhered to. Every patient undergoing joint surgery can have access to world best practice standards.

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What is Osteoporosis?

Osteoporosis happens when bone density decreases and the body stops producing as much bone as it did before.
It can affect both males and females, but it is most likely to occur in women after menopause, because of the sudden decrease in estrogen, the hormone that normally protects against osteoporosis.

As the bones become weaker, there is a higher risk of a fracture during a fall or even a fairly minor knock.

Osteoporosis currently affects over 53 million people in the United States (U.S.).

Fast facts on osteoporosis
Here are some key points about osteoporosis. More detail is in the body of this article.
Osteoporosis affects the structure and strength of bones and makes fractures more likely, especially in the spine, hip, and wrists.
It is most common among females after menopause, but smoking and poor diet increase the risk.
There are often no clear outward symptoms, but weakening of the spine may lead to a stoop, and there may be bone pain.
A special x-ray-based scan, known as DEXA, is used for diagnosis.

Treatments include drugs to prevent or slow bone loss, exercise, and dietary adjustments, including extra calcium, magnesium and vitamin D.

What is osteoporosis?
“Osteoporosis” literally means “porous bones.” The bones become weaker, increasing the risk of fractures, especially in the hip, spinal vertebrae, and wrist.

Bone tissue is constantly being renewed, and new bone replaces old, damaged bone. In this way, the body maintains bone density and the integrity of its crystals and structure.

Bone density peaks when a person is in their late 20s. After the age of around 35 years, bone starts to become weaker. As we age, bone breaks down faster than it builds. If this happens excessively, osteoporosis results.

Treatment of osteoporosis
Treatment aims to:

slow or prevent the development of osteoporosis
maintain healthy bone mineral density and bone mass
prevent fractures
reduce pain
maximize the person’s ability to continue with their daily life
This is done through preventive lifestyle measure and the use of supplements and some drugs.

Drug therapy
Drugs that can help prevent and treat osteoporosis include:

Bisphosphonates: These are antiresorptive drugs that slow bone loss and reduce fracture risk.
Estrogen agonists or antagonists, also known as selective estrogen-receptor modulators, SERMS), for example, raloxifene (Evista): These can reduce the risk of spine fractures in women after menopause.
Calcitonin (Calcimar, Miacalcin): This helps prevent spinal fracture in postmenopausal women, and it can help manage pain if a fracture occurs.
Parathyroid hormone, for example, teriparatide (Forteo): This is approved for people with a high risk of fracture, as it stimulates bone formation.
RANK ligand (RANKL) inhibitors, such as denosumab (Xgeva): This is an immune therapy and a new type of osteoporosis treatment.
Other types of estrogen and hormone therapy may help.

The future of osteoporosis therapy?
In future, treatment may include stem cell therapy. In 2016, researchers found that injecting a particular kind of stem cell into mice reversed osteoporosis and bone loss in a way that could, potentially, benefit humans too.

Findings published in 2015 suggested that growth hormone (GH) taken with calcium and vitamin D supplements could reduce the risk of fractures in the long term.

Also in 2015, researchers in the United Kingdom (U.K.) found evidence that a diet containing soy protein and isoflavones may offer protection from bone loss and osteoporosis during menopause.

Scientists believe that up to 75 percent of a person’s bone mineral density is determined by genetic factors. Researchers are investigating which genes are responsible for bone formation and loss, in the hope that this might offer new ways of preventing osteoporosis in future.

Bone loss that leads to osteoporosis develops slowly. There are often no symptoms or outward signs, and a person may not know they have it until they experience a fracture after a minor incident, such as a fall, or even a cough or sneeze.

Commonly affected areas are the hip, a wrist, or spinal vertebrae.

Breaks in the spine can lead to changes in posture, a stoop, and curvature of the spine.

Causes and risk factors
A number of risk factors for osteoporosis have been identified. Some are modifiable, but others cannot be avoided.

Unavoidable factors
Non-modifiable risk factors include:

Age: Risk increases after the mid-30s, and especially after menopause.
Reduced sex hormones: Lower estrogen levels appear to make it harder for bone to reproduce.
Ethnicity: White people and Asians are more susceptible than other ethnic groups.
Bone structure: Being tall (over 5 feet 7 inches) or slim (weighing under 125 pounds) increases the risk.
Genetic factors: Having a close family member with a diagnosis of hip fracture or osteoporosis makes osteoporosis more likely.
Fracture history: Someone who has previously experienced a fracture during a low-level injury, especially after the age of 50 years, is more likely to receive a diagnosis.
Diet and lifestyle choices
Modifiable risk factors include:

eating disorders, such as anorexia or bulimia nervosa, or orthorexia
tobacco smoking
excessive alcohol intake
low levels or intake of calcium, magnesium, and vitamin D, due to dietary factors, malabsorption problems, or the use of some medications
inactivity or immobility
Weight-bearing exercise helps prevent osteoporosis. It places stress on the bones, and this encourages bone growth.

Drugs and health conditions
Some diseases or medications cause changes in hormone levels, and some drugs reduce bone mass.

Diseases that affect hormone levels include hyperthyroidism, hyperparathyroidism, and Cushing’s disease.

Research published in 2015 suggests that transgender women who receive hormone treatment (HT) may be at higher risk of osteoporosis. However, using anti-androgens for a year before starting HT may reduce this risk. Transgender men do not appear to have a high risk of osteoporosis. More research is needed to confirm this.

Conditions that increase the risk include:

cancer
COPD
chronic kidney disease
some autoimmune diseases, such as rheumatoid arthritis and ankylosing spondylitis
Medications that raise the risk include:

glucocorticoids and corticosteroids, including prednisone and prednisolone
thyroid hormone
anticoagulants and blood-thinners, including heparin and warfarin
protein-pump inhibitors (PPIs) and other antacids that adversely affect mineral status
some antidepressant medications
some vitamin A (retinoid) medications
thiazide diuretics
thiazolidinediones, used to treat type 2 diabetes, as these decrease bone formation
some immunosuppressant agents, such as cyclosporine, which increase both bone resorption and formation
aromatase inhibitors and other treatments that deplete sex hormones, such as anastrozole, or Arimidex
some chemotherapeutic agents, including letrozole (Femara), used to treat breast cancer, and leuprorelin (Lupron) for prostate cancer and other conditions
Calcium is essential for bones, and ensuring an adequate calcium intake is important.

Adults aged 19 years and above should consume 1,000 milligrams (mg) a day. Women aged 51 years and over, and all adults from 71 years should have a daily intake of 1,200 mg.

Dietary sources are preferable and include:

dairy produce, such as milk, cheese, and yogurt
green leafy vegetables, such as kale and broccoli
fish with soft bones, such as tinned salmon and tuna
fortified breakfast cereals
If a person’s dietary intake is not enough, supplements are an option. Calcium supplements are available for purchase online.

Vitamin D plays a key role, as it helps the body absorb calcium. Dietary sources include fortified foods, saltwater fish, and liver.

However, most vitamin D does not come from food but from sun exposure, so moderate, regular exposure to sunlight is recommended.

Vitamin D supplements are available for purchase online.

Lifestyle factors for preventing osteoporosis
Other ways to minimize the risk are:

not smoking, as this can reduce the growth of new bone and decrease estrogen levels in women
limiting alcohol intake, to encourage healthy bones and prevent falls
getting regular weight-bearing exercise, such as walking, as this promotes healthy bone and strengthens support from muscles
doing exercises to promote flexibility and balance, such as yoga, as these can reduce the risk of falls and fractures

https://www.medicalnewstoday.com/articles/155646.php

(Image: Representation only)

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