A caucasian senior woman in a doctors office. She has white hair and is wearing a blue top. She is sitting in the examination room with an asian nurse holding a clipboard. She is holding a hand to her chest and looking uncomfortable. She is experiencing chest pains. The nurse is touching the patients shoulder to comfort her.
Older adults with higher levels of a thyroid hormone may be at an increased risk of artery disease and consequent death, according to new research. Free thyroxine (known as FT4) is a hormone produced by the thyroid gland that helps control the rate at which the body uses energy. Previous research linked the hormone to risk of irregular heartbeats.
The findings showed that elderly with high levels of FT4 hormone may be at twice the risk of having high levels of coronary artery calcification scores, which may be an indicator of atherosclerosis — the process of progressive thickening and hardening of the walls of arteries from fat deposits on their inner lining.
“We expected that thyroid function would influence the risk of developing atherosclerosis by affecting cardiovascular risk factors such as blood pressure. However, our results remained very similar after accounting for several cardiovascular risk factors,” said lead author Arjola Bano, from Erasmus University in the Netherlands. “This suggests that mechanisms other than traditional cardiovascular risk factors may play a role,” Bano added. Further, increasing FT4 levels were associated with 87% greater risk of suffering an atherosclerosis-related cardiovascular event as well as double the risk of atherosclerosis-related cardiovascular death. “Our findings suggest that thyroid hormone FT4 measurement can help identify individuals at increased risk of atherosclerosis,” Bano said.
For the study, detailed in the journal Circulation Research, the team analysed data from 9,420 participants with an average age of 65. They looked at data on two types of hormones: thyroid-stimulating hormone and free thyroxine (known as FT4) and their link to atherosclerosis and death due to coronary heart disease, cerebrovascular disease or other artery-related illness.
00seshunarayanahttps://imedworks.com/wp-content/uploads/2020/09/MedWorks-Logo-02-300x300.pngseshunarayana2020-08-07 11:00:282020-08-07 11:00:28Senior citizens, beware: High thyroid hormone levels can increase risk of heart disease
Endocrinology is a field in biology and medicine that deals with the endocrine system. The organs involved in the endocrine system include the pituitary, thyroid, adrenals, ovaries, testes and pancreas. These glands secrete hormones into the blood. Hormones of the endocrine system perform a variety of functions, and some hormones may have different effects depending on which organ is targeted. Organs may be targeted by a number of different hormones.
Endocrinopathy or endocrinosis are the terms used for diseases of the endocrine system. However, these conditions are often called hormone imbalances. Endocrinology may involve diagnosing and treating diseases of this system. Diagnosis often encompasses evaluating for a variety of symptoms and requires knowledge of clinical chemistry and biochemistry. Many laboratory tests also are used, including diagnostic imaging. Managing these diseases often requires long-term treatment and may involve treating the patient as a whole and maintaining observation of changes at the cellular or molecular level.
Endocrinologists must deal with many systems within the body, and researchers in the endocrinology field have tried to determine how the glands work. Researchers have also developed new drugs and treatments for hormone problems.
Other concerns of endocrinology include the integration of developmental events such as proliferation, growth and differentiation. Processes of differentiation may include histogenesis and organogenesis. Endocrinology also entails the coordination of many of the body’s systems, including metabolism, respiration, excretion, movement, reproduction and sensory perception. These systems may be examined on a chemical or cellular level and are observed based on chemical cues and secretions by various organs within the body.
Diseases, treatments
Endocrine diseases are caused when hormone levels are too high or too low, or when the body does not react to hormones the way it is supposed to.
The most common endocrine disease in the U.S. is diabetes. However, other conditions treated within endocrinology include osteoporosis, menopause, obesity, short stature, thyroid disease, hypertension and infertility.
Treatments typically involve controlling the amount of hormone the body produces, and, in cases of hormone deficiency, the use of hormone supplements.
Fast facts on endocrinology
Here are some key points about endocrinology. More information is in the main article.
Endocrinology involves a wide range of systems within the human body.
The endocrine tissues include the adrenal gland, hypothalamus, ovaries, and testes.
There are three broad groups of endocrine disorders.
Polycystic ovary syndrome is the most common endocrine disorder in women.
Diseases
A hormone imbalance can result from genetic or environmental factors.
Some infants are born with hormonal problems that can lead to a range of health issues, such as low growth.
Endocrine-disrupting chemicals, such as pesticides, lead, and phthalates, which are used in plastic food containers, can sometimes lead to hormonal problems.
There are three broad groups of endocrine disorders:
A gland does not produce enough of its hormones. This is known as endocrine gland hyposecretion
A gland produces too much of its hormones, also referred to as hypersecretion.
Tumors develop in the endocrine glands. They may be malignant, or cancerous, but they may also be benign, or non-cancerous.
What can go wrong?
Here are some examples of what can happen if a gland secretes too much or too little of its hormones.
Adrenal Gland
Hypersecretion may lead to over-nervousness, sweating, raised blood pressure, and Cushing’s disease
Hyposecretion may lead to Addison’s disease, Mineralocorticoid deficiency, weight loss, loss of energy, and anemia.
Pancreas
Hypersecretion may lead to hyperinsulinism, too much insulin can lead to low blood glucose
Hyposecretion may lead to one type of diabetes
Parathyroid Gland
Hypersecretion may lead to brittle bones that fracture easily, as well as stones in the urinary system
Hyposecretion may lead to involuntary muscle contractions, or tetany, caused by low levels of calcium in plasma
Thyroid Gland
Hyperthyroidism most often stems from Graves’ disease. It can lead to accelerated metabolism, sweating, arrhythmia or irregular heart beat, weight loss, and nervousness.
Hypothyroidism may lead to tiredness, weight gain, depression, abnormal bone development, developmental delay, and stunted growth.
Pituitary Gland
Hypersecretion may lead to gigantism, or excessive growth
Hyposecretion may lead to slow bone growth and short stature
Thymus Gland
Hypersecretion may lead to an overactive immune system which overreacts to perceived threats. This may result in an autoimmune disease.
Hyposecretion may lead to a weakened immune system, where the body is unable to fight infection and easily succumbs to viruses, bacteria, and other pathogens.
00seshunarayanahttps://imedworks.com/wp-content/uploads/2020/09/MedWorks-Logo-02-300x300.pngseshunarayana2020-07-23 20:58:272020-07-23 20:58:27What is endocrinology?
