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Two in one? New pill may curb type 2 diabetes and aid weight loss

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The study was conducted by a team from Leicester Diabetes Centre. Patients who were taking Metformin were given the pill.

Diabetes is considered to be a silent killer by medical professionals across the world. Even a single symptom reflecting the onset of the disease is a cause for concern.

It is a disease that could be hereditary and can also develop due to an unhealthy lifestyle.

Semaglutide is reportedly the first pill to help incite weight loss, according to a report by the Daily Mail. 71% of the 632 patients in the study were able to loose weight test results revealed.

The study was conducted by a team from Leicester Diabetes Centre. Patients who were taking Metformin were given the pill.

There are many medically prescribed ways and means to ensure prevention from developing the potentially lethal disease and those who are at immediate risk, are often advised diet control.

Researchers are hoping the new pill can control the common condition as some of the treatment currently available provokes weight gain and worsens type 2 diabetes. The pills also stopped patients from needing insulin.

The pill could offer a relief for those who struggle with injecting themselves. “For some patients injectable therapies are a problem, so having something available orally makes it more accessible to some patients,” lead author Professor Melanie Davies told the Daily Mail.

Type 2 diabetes is deadly as it can cause heart failure, blindness and leg amputations. “Type 2 diabetes is a serious condition with potentially devastating complications which is posing a major challenge to health services across the world because of the increasing numbers of people developing it,” Professor Davies told the Daily Mail.

Many experts are enthusiastic about the findings. “These latest results are hugely encouraging and will be welcomed across the diabetes community,” Oliver Jelley, editor of The Diabetes Times told the Daily Mail.

The findings were published in the JAMA.

Source: http://zeenews.india.com/health/two-in-one-new-pill-may-curb-type-2-diabetes-and-aid-weight-loss-2050837

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A new way to lose fat. Freezing this nerve can kindle weight loss

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Turns out, freezing a nerve can ignite weight loss.

According to a study led by the Society of Interventional Radiology, freezing the nerve that carries hunger signals to the brain may help mild-to-moderate obese patients lose weight. The treatment was determined safe and feasible in the initial pilot phase.

“We developed this treatment for patients with mild-to-moderate obesity to reduce the attrition that is common with weight-loss efforts,” said David Prologo, lead author of the study. “We are trying to help people succeed with their own attempts to lose weight.”

This nerve, located at the base of the esophagus, is one of several mechanisms that tell the brain the stomach is empty. In the study, 10 subjects with a BMI between 30 and 37 underwent the procedure and were followed for 90 days.

During the procedure, an interventional radiologist inserts a needle through the patient’s back and, guided by live images from a CT scan, uses argon gas to freeze the nerve, known as the posterior vagal trunk.

This nerve, located at the base of the esophagus, is one of several mechanisms that tell the brain that the stomach is empty. In the study, 10 subjects with a Body Mass Index (BMI) between 30 and 37 underwent the procedure and were followed for 90 days. All subjects reported decreased appetite and the overall average weight loss was 3.6% of initial body weight and an average decline of nearly 14% of the excess BMI.

No procedure-related complications were reported, and there were no adverse events during the follow up.

“Medical literature shows the vast majority of weight-loss programs fail, especially when people attempt to reduce their food intake,” said Prologo. “When our stomachs are empty, the body senses this and switches to food-seeking survival mode. We’re not trying to eliminate this biological response, only reduce the strength of this signal to the brain to provide a new, sustainable solution to the difficult problem of treating mild obesity.”

Following the success of this preliminary safety and feasibility study, more patients are being recruited for a larger clinical trial of the procedure to test the efficacy and durability of the procedure.

In presenting the study, the authors noted several limitations, including the small sample size and the interim nature of the results. The findings from the study are presented at the Society of Interventional Radiology’s 2018 Annual Scientific Meeting.

Source: https://www.hindustantimes.com/health/a-new-way-to-lose-fat-freezing-this-nerve-can-kindle-weight-loss/story-i1L9ztAKdggAIW3b1W70bI.html

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